Involvement of Helicobacter Pylori in the Genesis of Precancerous Stomach Lesions: Epidemiological Aspects Based on an Algerian Study

Abstract

1. Abstract
Helicobacter Pylori is a bacterium involved in the genesis of precancerous lesions of the stomach. This infection is universally prevalent but is higher in developing countries. A retrospective study spread over 3 years (2018-2019-2020) was conducted at the pathological anatomy laboratory of the Chadli Bendjedid Hospital in El Tarf, northeast Algeria. All patients were submitted to a fiberscope, and the diagnosis was established by histological examination. The results show that of the 134 patients examined, 100% were diagnosed with chronic gastritis. The prevalence of H. pylori infection was 61.94%; 63.86% of women were affected, and the most susceptible age group was 50-59 years; 36.14% of men were affected, mainly in the age group 30-39 years. Locally, the fundic antrum area appeared to be the most affected (81.93%) with moderate chronic atrophic gastritis (78.57%) and silent activity (94.28%), which favors the development of cancer cells.