Abstract

1. Abstract
Pregnancy combined with lithium carbonate poisoning is a great threat to pregnant women, and there is no specific antidote. A woman in the third trimester of pregnancy with fatigue, polydipsia, anorexia, tremor in both hands, acute renal insufficiency, and multiple organ dysfunction was admitted to our hospital. The possibility of poisoning was considered, and fluid rehydration and diuresis were given. Then the family members provided that the patient had a history of schizophrenia and took lithium carbonate sustained release tablets orally for a long time during pregnancy. Laboratory tests showed that the blood concentration of lithium was 1.46mmol/L, which exceeded the normal range, and confirmed lithium poisoning. On the second day of drug withdrawal, the blood concentration of lithium was normal, and the discomfort symptoms and abnormal signs disappeared. This case suggests that lithium poisoning may occur after long-term use of lithium carbonate in pregnancy complicated with psychosis. After symptomatic treatment, the maternal and infant outcomes are good after timely termination of pregnancy.