Abstract

1. Abstract
Epithelial- Myoepithelial Carcinoma (EMC) is a rare biphasic salivary glands tumor with low malignant potential. Pathohistological Differential Diagnosis (DD) is difficult due to the rare frequency and biphasic cell characteristic of the EMC, which requires Immunohistochemical (IHC) analysis to define the epithelial and myoepithelial cell component. In the article we present a clinical case at a 55 -year -old woman with a rarely diagnosed EMC of submandibular salivary gland, in which a local tumor excision with postoperative radiotherapy (RT) was performed. Strict diagnosis requires a wide immunohistochemical analysis. Despite the low -malignant tumor characteristics, EMC requires radical surgical resection with clean resection lines.