Micronized Amniotic Membrane for Dry Eye Disease: ACase Series

Abstract

1. Abstract
Dryeye disease is common and affects millions of people throughout the world. Unfortunately, the management of this disease can be challenging due to persistent inflammation and damage to the ocular surface which can result in ocular discomfort, photophobia, and blurred vision. Herein, we report the outcome of three patients with moderate dry eye disease that was recalcitrant to conservative treatments including artificial tears, ophthalmic immunomodulator
drops, and topical lubricants. All patients presented with superficial punctate keratopathy (1+ to 3+ SPK), moderate ocular pain (5-6 out of 10), and were subsequently treated with micronized amniotic membrane applied with a bandage contact lens for 3-4 days. After treatment, the patients reported no pain (0 of 10) and there was faint SPK. At 1 month, SPK had resolved and the patients’ visual acuity was 20/20. This case series highlights the utilization of micronized amniotic membrane with a bandage contact lensto manage patients with moderate dryeye disease.