Abstract

1. Abstract
Medulloblastoma (MB) is the most common malignant brain tumour in children. Despite the complex therapy, including a visible total surgery, cranio-spinal radiotherapy (CSRT) with boost in tumor bed and adjuvant chemotherapy (Ch), there are late local recurrences with poor prognosis. We present a 9-year old boy with local medulloblastoma recurrence three years after subtotal tumor resection, CSRT and Ch. The objective of the article is to highlight the importance of total re-surgery with subsequent cranio-spinal re-irradiation with tumor bed boost in children with late local medulloblastoma recurrence. In disease progression, regardless of recurrence, local or metastatic in cranio-spinal axis, the combination of the two local methods re-surgery followed by re-irradiation improve the outcome of recurrent MB children.