Small Bowel Adenocarcinoma in Celiac Disease

Abstract

1. Abstract
Celiac disease is defined as a chronic immune disorder triggered by gluten ingestion. It results in damage of intestinal lining and causes diarrhea, fatigue, weight loss, bloating and anemia. It is estimated to affect 1 in 100 people worldwide (9) and incidence of small bowel carcinoma (SBA) is extremely rare (5). It can occur in a sporadic form or can be associated with a number of predisposing conditions such as hereditary syndromes and immune-mediated intestinal disorders, e.g., celiac disease (CD). However, the features of SBA in the context of CD remain not well understood. Herein we are reporting a case of CD with small bowel adenocarcinoma 41- year-old female patient whom diagnosed with celiac disease for 2 years. Followed over this period with the gastroenterology with progressive symptoms of abdominal pain, nausea and vomiting. Investigations showed segment of bowel with the mass and elements of partial bowel obstruction. The biopsy revealed invasive adenocarcinoma which she underwent surgical resection.