
Breast cancer has been the greatest threat to female all over the world. There are various therapies to cure this common disease, such as surgery, chemotherapy, radiotherapy, immunotherapy and so on. Implantable Venous Access Port has been widely used in breast cancer chemotherapy. We found two patient had Persistent Left Superior Vena Cava accidently, while had PORT implanted via their internal jugular vein. The purpose of this article is to introduce our two rare cases and review relative literature.