Abstract

1. Abstract

Forward participation of ongoing reformulation of tumor neoantigenicity is paramount consideration in the genesis of DC immaturity in the tumor microenvironment. In such terms, the hierarchical nature of DC migration abnormalities includes the patterns of interactivities of the innate with the adaptive immune systems as proposed by theoretical aspects of abnormal chemokine action. The various suppressive factors released by tumor cell pools call into consideration a relativity process of failed antigen processing and presentation by immature DC.