The Stomach: An Uncommon Site for Metastatic Breast Cancer

Abstract

Metastatic breast cancer to the gastrointestinal tract is uncommon with metastasis to the stomach being even more rare, with gastric metastases recognized in only 0.3-18% of patients with Stage 4breast cancer [1]. However it is important to recognize this subtle presentation as diagnosis alters prognosis and treatment approach [2]. Metastasis to the gastrointestinal tract is more commonly seen in ILC compared to IDC, which are biologically and morphologically distinct from each other, with the lack of E-cadherin in ILC postulated as the reason for this phenomenon [3].