
Acute Renal Cortical Necrosis (ARCN) is characterized by the destruction of the renal cortex with poor prognosis. Here, we reported a Chinese female patient presenting abrupt anuria, acute kidney injury and heart failure. Examination revealed proteinuria, hematuria, anemia, thrombocytopenia, acute renal injury and acute left heart failure. Serologic tests showed positive antinuclear antibody, positive anti-doublestranded DNA antibody, positive antiphospholipid antibody, and low serum complement C3 level. Magnetic resonance imaging confirmed the diagnosis of ARCN.